Los Angeles police say the shooting happened around 6:45 p.m. in the 700 block of S. Spring Street.
Two men got into a verbal argument, leading to the suspect shooting the victim, police say.
The victim, a man in his 30s, was pronounced dead at the scene.
Police say the suspect ran away after the shooting. He is believed to be in his 30s.
A handgun was recovered at the scene.
Further details into the shooting were not immediately released.