It was not immediately clear when or where the pursuit began, however, Scott Reiff said AIR7 HD began tracking the chase in the Monterey Park area, where the driver of the pickup truck jumped from the 10 Freeway to the 110 Freeway, reaching speeds up to 100 mph.
AIR7 HD was over the chase around 10:30 a.m. as the driver sped along residential streets, blowing through intersections and quickly turning corners.
The male driver, who had a female passenger in the vehicle, circled around the area of S. Central Avenue with at least three Los Angeles police cruiser following closely behind.
Authorities switched several times from tracking mode to an active pursuit.
Police chase: Wrong-way driver slams into innocent motorist on 110 Fwy. in South L.A.
Police chase: Wrong-way driver slams into innocent motorist on 110 Fwy. in South L.A.
At one point, a sedan driving on a street quickly got out of the way of the pickup truck as the driver came close to the vehicle's back bumper.
About 15 minutes later, the driver appeared to lose control of the truck, swerving in front of a police cruiser on a residential street before regaining control and continuing down the roadway.
Truck avoids spike strips during high-speed chase in Los Angeles
The vehicle, which climbed to speeds of 80 mph, skidded to a stop on S. San Pedro Street - just in time to avoid a spike strip deployed by officers near an intersection.
The dangerous pursuit continued onto the southbound 110 Freeway around 11 a.m.
Shortly after, the driver attempted to exit the freeway, spinning out and striking an exit sign before continuing northbound on the shoulder of the southbound lanes.
The truck narrowly missed several vehicles while driving against oncoming traffic before running head-on into a sedan. The suspect briefly paused before driving off of a freeway on-ramp.
The bizarre scene continued as a pedestrian on a residential street ran up to the vehicle and appeared to hand the passenger a bottle. It was unclear the man's connection to the suspects or what was in the bottle.
A driver who was also in a pickup truck appeared to attempt to block the suspect near E. Florence Avenue. Smoke began to emit from the back of the vehicle as the suspect rammed into the other truck before pushing past and continuing on to Florence.
WATCH: Pickup truck driver blocks suspect during police chase through South LA
Pickup truck driver blocks suspect during police chase through South LA
Moments later, the rear tire on the driver side blew. The suspect continued on residential streets while driving on the rim at slower speeds.
The worn-down rim caught fire near S. Main Street, where the driver and passenger jumped out of the vehicle and were quickly taken into custody as multiple officers descended on the scene just before noon.
WATCH: Suspected stolen vehicle suspect taken into custody following high-speed chase through South LA
Suspected stolen vehicle suspect taken into custody following high-speed chase through South LA