Los Angeles police responded to the scene around 9:25 p.m. in the 600 block of North Wilton Place.
Responding officers found one female stabbing another female, according to LAPD.
The victim was pronounced dead at the scene and the suspect was taken into custody, police said.
Additional information on the victim was not immediately released.
No officers were injured.
Investigators said it was unclear why the stabbing occurred, but according to the preliminary investigation, detectives do not believe the incident was connected to nearby protests related to the in-custody death of George Floyd.
City News Service contributed to this report.