The book, "Becoming," is set to be released Nov. 13. She will appear at the Forum on Nov. 15 and finish the tour in Dallas in December.
The former first lady tweeted out a video from her office talking about her book and 10-city tour.
"I am proud because it is candid, it's honest, it's totally and utterly me, so I'm also a little frightened because it is so candid and honest and open, but I can't wait to share it with the world," Obama said.
Crowds are expected to be too big for any bookstore to accommodate.
The tour will begin in her native Chicago.