Los Angeles County deputies were called to the 9100 block of Rosecrans Avenue at 3:18 p.m.
They found a woman who had apparently been shot. She was pronounced dead at the scene.
They also found a man, described as a suspect, who had a gunshot wound. He was transported to a local hospital and his condition was not released.
Officials said the incident appeared to be a murder-attempted suicide, but they were continuing to investigate.