The collision happened just before 2:30 a.m. at Norwalk Boulevard, according to the California Highway Patrol. Officials say multiple vehicles were involved, but it's unknown exactly how many.
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Three people were found dead at the scene and two others were taken to the hospital in unknown condition.
Multiple freeway lanes were shut down as a result of the deadly crash, the cause of which remains under investigation.
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DEVELOPING: We will add more details to this report as they become available.