Jennifer Aniston stars as an uptight CEO who cancels the company Christmas party, but her brother, played by T.J. Miller, throws a wild shindig anyway.
"You're in for a lot of fun, a lot of laughter and a lot of great comedic talent," Aniston said.
The film also features Kate McKinnon, Jason Bateman, Olivia Munn, Vanessa Bayer and Courtney B. Vance.
For more on the R-rated film - which opens Friday - and what its stars said at the premiere, watch the video above.