Investigators later determined the man was holding a realistic-looking airsoft rifle.
Officers were called for a domestic violence report to a home in the area of 102nd and Grand streets around 1:20 p.m. Saturday.
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Two officers responded to the scene. Los Angeles Police Department officials say a man came out of the home armed with a weapon, appearing to be a type of rifle.
The exact nature of the confrontation with officers was not detailed and remains under investigation, but he was shot and later declared deceased at the scene. It is also unclear if one or both officers opened fire.
The man is believed to be in his late teens or early 20s.
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After the shooting, investigators examined the rifle and determined it was an airsoft.
LAPD officers shoot, kill man brandishing rifle after family disturbance in South Los Angeles
There were no other injuries reported in connection with the incident. The LAPD is launching its standard procedures for officer-involved shootings, which include review by the Force Investigation Division, the police chief and police commission.