Police said the woman, who has not yet been identified, was parked on the south side end of Pearson Park on North Harbor Boulevard.
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The tree came crashing down at around 3 p.m. and landed on top of a maroon-colored Ford SUV with her inside.
"Upon officers' and fires' arrival, they located a woman in the backseat, trapped under the large tree," said Anaheim PD Sgt. John McClintock.
The woman was pronounced dead on the scene. She was the only person inside the vehicle, according to police.
Police said she was at the park with family members though it's unclear if they witnessed the incident.
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Crews worked into the evening to remove the tree.
It's unclear what caused the tree to fall.