The crash was reported in the 600 block of La Peer Drive, near the busy L.A. Pride Festival, where tens of thousands of people attended a march just hours earlier.
Officials at the scene said a white Mercedes-Benz pulled out of a driveway and hit the three pedestrians.
The victims were initially reported to have minor injuries, but it was later reported they were transported to Cedars-Sinai Medical Center. There was no update on their conditions.
The driver of the Mercedes-Benz remained at the scene and was being investigated for possible DUI.