The fire was reported just after noon near the interchange of the 10 Freeway and the 57 Freeway, according to the California Highway Patrol.
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AIR7 HD was above the fire as crews were working to extinguish the blaze.
A large plume of smoke could be seen above the freeway, though no structures in the area were threatened, authorities said.
Portions of the road were shut down.
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No injuries have been reported.
Drivers in the area are urged to avoid the area and seek an alternate route.