The two people killed in the crash were identified as 19-year-old Bryan Bolaños and 18-year-old Carlos Sicairos.
The violent collision occurred shortly before 3 a.m. at the Nash Street offramp of the westbound 105 Freeway.
One of the cars with at least three people inside fell from the offramp and landed on another car in the parking of the airport's FedEx parking lot, according to CHP.
The cause of the crash remains under investigation.