Diane Sawyer's most iconic interviews through the years

NEW YORK -- The beloved and tenured journalist Diane Sawyer announced that she would leave ABC's World News anchor desk Wednesday morning. However, Diane will still remain at ABC News to conduct the special, high-profile interviews of which she is famous worldwide for. Throughout her career, Sawyer has interviewed some of the world's most renowned and influential leaders, celebrities, and controversial news figures. Here are some of her most iconic interviews:

Amanda Knox

Sawyer has an emotional conversation with now convicted murderer Amanda Knox.

Whitney Houston

The dearly departed pop singer candidly discusses her drug use with Sawyer.

Michael Jackson

Sawyer asks the King of Pop hard questions about his legal battles and bizarre behavior around children.

Mel Gibson

Gibson opens up about his drinking and controversial anti-Semitic remarks to Sawyer.

Charles Manson

The infamous mass murderer rants to Sawyer.

George W. Bush

The 43rd President discusses terrorism and lessons learned during his time in office.