Rappers Ice-T and Fat Joe are set to speak at the 11:30 a.m. ceremony at 6126 Hollywood Blvd., near Gower Street, which will be hosted by radio personality Big Boy.
The group's members -- Krayzie Bone (Anthony Henderson), Layzie Bone (Steven Howse), Bizzy Bone (Bryon Anthony McCane II), Wish Bone (Charles C. Scruggs Jr.) and Flesh-n-Bone (Stanley Howse) will make brief acceptance speeches, Ana Martinez, producer of the Hollywood Walk of Fame, told City News Service.
Steven and Stanley Howse are bothers and cousins of Scruggs.
The ceremony comes two days before the group begins a concert tour at the Garden Amp in Garden Grove.
The star is the 2,851st since the completion of the Walk of Fame in 1961 with the initial 1,558 stars.
Formed in Cleveland in 1991 as B.O.N.E. Enterpri$e, the group became famous for its blend of rapid-fire rap delivery, melodic harmonies and emotional storytelling.
They were discovered by rapper Eazy-E of NWA fame, who was impressed by their style and signed them to Ruthless Records in 1993 and helped launch their national career.
Their breakthrough came with the 1994 extended play "Creepin on ah Come Up," featuring hits such as "Thuggish Ruggish Bone" and "Foe tha Love of $." The project introduced audiences to their fast-paced flows and harmonized vocals.
The group had its first No. 1 hit in 1995, "E 1999 Eternal," which topped both Billboard's U.S. chart and the R&B/Hip-Hop Albums chart.
The group's next album, "The Art of War," released in 1999, also topped both charts, while its third album, "BTNHResurrection," released in 2000, topped the R&B/Hip-Hop Albums chart and was second on the U.S. chart.
Bone Thugs-N-Harmony received its first Grammy nomination in 1996. "E. 1999 Eternal" was nominated for best rap album. The single "1st of tha Month," from "E. 1999 Eternal," was nominated for best rap performance by a duo or group.
"Tha Crossroads," a tribute to Eazy-E after his death in 1995, became a worldwide hit, spending eight weeks at No. 1 on the Billboard Hot 100 and won the Grammy for best rap performance by a duo or group in 1997.
"Receiving a star on the Hollywood Walk of Fame is a blessing beyond words," the group said in a statement. "Coming from Cleveland, we never imagined that the music we created would touch so many lives around the world.
"This honor belongs not only to Bone Thugs-N-Harmony, but to our families, our city, our fans, and everyone who believed in us from the beginning. More than three decades later, we're still here, still creating, and still carrying the legacy forward."