The crash was reported at 10:55 p.m. Saturday and responding personnel found one person dead under the tanker truck, LAFD spokeswoman Margaret Stewart said.
The driver of the tanker was reportedly transported to the hospital by private vehicle and had no contact with LAFD responders, she added. A 30- year-old woman was transported by paramedics to a hospital with minor injuries.
Firefighters used a redwood plug to stop a leak in the tanker, where an estimated 8,000 gallons of aviation fuel remained, Stewart said.
Both sides of 110 Freeway in South L.A. closed after deadly tanker truck crash
LAFD crews assisted Caltrans with laying down an absorbent to contain the fuel hazard, authorities said.
Firefighters drilled four holes into the tanker to give access for the fuel offload operation, which was conducted by the owner of the truck company.
Private wreckers were at the scene to upright the tank trailer and prepare it for removal. Firefighters will extricate the victim and assist the L.A. County Medical Examiner's office with recovering the body.
The California Highway Patrol issued a SigAlert at 11:10 p.m. Saturday closing the northbound and southbound lanes of the Harbor (110) Freeway, at Manchester Boulevard. The closure for the southbound lanes ended at 7 a.m. and the closure for the northbound lanes ended at 12:20 p.m., according to the CHP.