The incident unfolded around 7:20 p.m. Saturday at the 14300 block of Foothill Boulevard.
According to police, a suspect, described only as a man in his 30s, carjacked a vehicle and crashed into at least three other vehicles while fleeing.
One victim from that crash was transported in unknown condition.
The suspect then ran into oncoming traffic and was struck. He was transported to the hospital in unknown condition and will be booked for grand theft auto.
No further information was immediately available.
While police investigated that carjacking crash, another incident unfolded in Sylmar.
A suspected DUI driver crashed into a police cruiser that was blocking Foothill Boulevard and Tyler Avenue.
It was reported at around 9:30 p.m. while two officers were outside their vehicle blocking off traffic for the carjacking investigation down the street on Foothill Boulevard.
The driver ignored them and crashed into the police cruiser.
The suspect was taken into custody. No officers were injured.