Officers initiated the pursuit on the southbound side of the freeway at Martin Luther King Boulevard for a vehicle with mismatching plates around 3:30 a.m., according to the Los Angeles Police Department.
The chase only lasted about a minute before the suspect crashed on the freeway at Vernon Avenue.
Police say a person was ejected from the vehicle, but could not confirm if it was the suspect.
Video from the scene shows the suspect being treated by first responders.
DEVELOPING: We will add more details to this report as they become available.