The incident happened around 4 a.m. at Tampa Avenue, according to the California Highway Patrol's traffic log.
It's unclear what caused the crash, but one semi overturned and the other was left jackknifed as a result. AIR7 was over the scene where a load of what appeared to be bricks were scattered across several lanes.
At one point, all westbound lanes were shut down as crews worked to clear the wreck. The far right lane was eventually reopened, but the rest were expected to remain closed until further notice.
DEVELOPING: We will add more details to this report as they become available.