Deputies responded just after 9 p.m. to the 10400 block of Artesia Boulevard following a report regarding an assault with a deadly weapon suspect, according to sheriff's officials.
At some point during the encounter, deputies opened fire on the suspect. The man was shot and taken to a hospital where he was pronounced dead.
No additional information about the circumstances leading up to the confrontation was immediately available.
Aerial footage from AIR7 showed a blood-soaked sidewalk and a detective shining a flashlight on a handgun lying on the ground. The footage also captured multiple evidence markers and bullet casings scattered nearby.
No deputies were injured in the incident. An investigation is ongoing.