"I will win this battle," Vitale said on X.
Vitale was previously diagnosed with lymphoma in his neck in 2021. After surgery in November of 2023, he said his vocal cord cancer "is gone."
Vitale said he will undergo surgery on Tuesday adding it "will be a success."
Vitale has been with ESPN since 1979, the year the network launched. He called ESPN's first college basketball broadcast.
Disney is the parent company of ESPN and this station.