The crash was reported around 3 a.m. at Frazier Street near the 605 Freeway, according to the California Highway Patrol's traffic log. The incident also shut down the northbound 605 Freeway transition to the eastbound 10 Freeway.
AIR7 was over the scene where crews were working to clear the wreck. The big rig was apparently carrying a load of onions.
Officials initially said the freeway would reopen around 5 a.m., but only two lanes were reopened by 6 a.m. By around noon, the freeway was fully reopened.