The theft happened around 5:30 a.m. Thursday at El Mariachi Mexican Grill in the 15600 block of Ventura Boulevard, according to the Los Angeles Police Department.
Video shows the suspects using a tool to crack open an inside door. When police arrived to the restaurant, the burglars had already fled.
The owner said the burglars took the restaurant's safe, along with a television and three bottles of tequila.