A shelter-in-place order is in effect for the area around Garfield Avenue and Imperial Highway.
Police asked people to avoid the area of Gardendale and Industrial streets to allow first responders to safely respond to the incident.
AIR7 video showed crews attacking the blaze from the roof and from ladders as they work to gain control of the second-alarm fire.
Aerial footage also showed a large plume of black smoke billowing over the area as crews continued their efforts.
The fire appeared to be near homes, though it was not immediately clear whether any other structures are threatened.
Some nearby residents have reported power outages. According to Southern California Edison, a fire-related power outage is impacting 493 customers near the fire.
The outage began just before 3:30 p.m. and power was expected to be restored around 5 p.m., according to SCE's website. However, as of 5:20 p.m., it still appeared as an active outage.
Further information was not immediately available.
This is a breaking news story. More details will be added as more information becomes available.