A 911 caller reported the crash shortly before 12:30 p.m. just east of the airport, according to the Ventura County Fire Department.
The pilot was airlifted to a trauma center. No other injuries were reported.
A photo provided by the Fire Department showed the charred wreckage of the single-engine plane. The intense fire incinerated most of the aircraft, leaving only its mangled frame near a trash dumpster.
The National Transportation Safety Board was notified and is expected to conduct an investigation into the cause of the incident.