AIR7 was over the scene just before 11 p.m. Friday as the driver sped on surface streets through the South Gate area and into the Florence neighborhood.
The driver then ran a red light and was hit by an oncoming car at an intersection in the area of Firestone Boulevard and Alameda Street.
The impact of the crash sent the suspects' car over a curb and into a minivan parked in front of a 7-Eleven.
Three suspects then jumped out of the car and tried to escape, but they were later taken into custody. The sheriff's department said the car was involved in a street takeover.
Details surrounding injuries is unknown.