The mission, dubbed Polaris Dawn, lifted off at 5:23 a.m. ET.
SpaceX livestreamed the event on X, the social media platform formerly known as Twitter that SpaceX CEO Elon Musk purchased in 2022.
As the capsule entered Earth's orbit, ground controllers, led by SpaceX launch director Frank Messina, offered words of encouragement to the Polaris Dawn crew, which includes the first SpaceX employees ever to venture to space.
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"As you gaze towards the North Star, remember that your courage lights the path for future explorers. We trust your skills, your bravery, and your teamwork to carry out the mission that lies ahead," they said. "Know that the entire team back here is with you every step, watching, supporting and cheering you on as you walk into space. We're sending you hugs from the ground."
This launch comes after several weather delays in late August and earlier in the morning on Tuesday hampered the Polaris Dawn crew's efforts to get off the ground.
Further complicating launch prospects was the fact that SpaceX didn't just need clear weather for the mission to take off - it needed to ensure there are calm waters and winds as the crew will return from space after a five-day excursion. Timing their return could be critical. Because carrying out a spacewalk will create a drain on oxygen supplies, the Polaris Dawn mission will have only enough life support for five or six days in space.
The ride to orbit
After the countdown clock struck zero, SpaceX's Falcon 9 rocket roared to life, sending a blinding blaze and deafening blast across the launch site at NASA's Kennedy Space Center in Florida.
The crew rode atop the rocket, strapped inside an igloo-shaped SpaceX Crew Dragon capsule, which measures about 13 feet (4 meters) across at its base, as the rocket tore away from the grips of Earth's gravity.
After firing for 2 minutes, the bottommost part of the Falcon 9 rocket - called the first stage - spent most of its fuel. At that point, the first stage detached from the rocket's second stage as the upper portion fired up its engine and continued propelling the Crew Dragon spacecraft to faster speeds.
Meanwhile, the first stage of the Falcon 9 guided itself back to Earth to land on a seafaring platform so it could be refurbished and used again on future missions. That's a signature SpaceX move that the company said helps reduce the cost of rocket launches.
To enter Earth's orbit, the Falcon 9 rocket hit more than 17,000 miles per hour (27,358 kilometers per hour), or "orbital velocity." When it reached the desired speed, the Crew Dragon broke away, navigating the vacuum of space using only its onboard thrusters for the remainder of the mission.
First commercial spacewalk attempt
Polaris Dawn is the brainchild of SpaceX and Jared Isaacman, the billionaire founder of financial technology firm Shift4 Payments, who made his first foray into spaceflight with the Inspiration4 mission in September 2021.
This flight, however, is not a joyride.
Isaacman and his crewmates - including close friend and former US Air Force pilot Scott "Kidd" Poteet as well as SpaceX engineers Anna Menon and Sarah Gillis - hope to rack up several superlatives on this mission.
First, the SpaceX capsule aims to carry the crew to record-setting heights for an orbit around Earth, surpassing the milestone set by NASA's 1966 Gemini 11 mission, which reached 853 miles (1,373 kilometers). If successful, Polaris Dawn would beat that record by about 20 miles (32 kilometers).
The Polaris Dawn spaceflight would also be the highest any human has flown since NASA's Apollo program - which ended in 1972 and cumulatively carried 24 astronauts a quarter million miles to the moon rather than stopping in Earth's orbit.
Polaris Dawn may also mark the farthest any woman has ever gone into space.
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To kick off day three of this mission, the civilian crew, while orbiting at a lower altitude of about 435 miles (700 kilometers) above Earth, will attempt a history-making spacewalk.
The endeavor will be hazardous, exposing all four crew members and the Crew Dragon's interior to the vacuum of space. Such a situation may make it difficult to relock the vehicle's hatch due to differences in pressure. And exposure to the vacuum may cause toxins to be released from hardware when the cabin is repressurized, though SpaceX said it has taken steps to prevent this.
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