The incident unfolded around 2 a.m. when police were called to a home on Wystone Avenue over a family dispute, according to the Los Angeles Police Department.
A victim police described as a brother was stabbed. They were taken to the hospital and are expected to be OK.
The suspect then barricaded himself inside and homes nearby were evacuated. It's unclear what their relationship to the victim is.
The suspect was taken into custody around 4 a.m.