The incident occurred at the intersection of Euclid and Valencia at approximately 9:51 a.m.
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Police said the suspect was driving a stolen SUV and hit a Honda with two people inside.
The passenger in the Honda was killed and the driver was transported with traumatic injuries, police said.
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The driver of the SUV was taken into custody on suspicion of driving a stolen vehicle.
Witnesses said the suspect was speeding and driving erratically.
Police later said the suspect was believed to have been driving under the influence of drugs.