The fire has burned 2,690 acres and is now 15% contained, according to fire officials.
AIR7 video from Saturday showed heavy smoke and pockets of active flames within the burn area as crews worked to strengthen containment lines around the fire.
More than 500 firefighters from Los Angeles County, San Bernardino County and the U.S. Forest Service have been battling the fire since it erupted Friday near Jesus Canyon Road and East Avenue Z, close to the Los Angeles-San Bernardino county line.
One firefighter suffered minor injuries while battling the blaze and is expected to recover, officials said.
Authorities said the fire has damaged one residence and destroyed one minor structure.
While cooler temperatures have helped firefighting efforts, officials warned that changing weather conditions in the high desert could still create challenges for crews working to contain the fire.
Evacuation orders have been lifted, though some evacuation warnings remain in effect in parts of Los Angeles County. Officials also said all evacuation notices have been lifted in San Bernardino County.
Hundreds of homes in Los Angeles County remain under evacuation warnings or orders.
The Red Cross has opened a shelter for those affected by the fire at the Antelope Valley YMCA on 10th Street East in Lancaster. Pets are welcome but must be kept in a travel carrier or pet crate.
A small animal shelter is also available at the Los Angeles County Animal Care Center-Palmdale, located at 38550 Sierra Highway.
The shelter is open 24 hours a day for residents displaced by the fire.
City News Service contributed to this report.