The video shows the driver of a white Honda Civic plow into a pickup truck. The truck then spins out of control, hitting another vehicle.
The crash happened on Sepulveda Boulevard near Nordhoff Street.
Authorities said at least two people were hurt, including the driver of the Civic.
The chase started around 7:34 a.m. on the northbound 405 Freeway, according to the California Highway Patrol. Officers attempted to pull over the white Honda Civic, which flew past one of its cruisers, reportedly reaching speeds up to 125 mph.
The CHP canceled the pursuit about four minutes later, shortly before the violent crash.