Police say about 20 people were renting a house and having a party when the armed men broke into the guest house.
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The Los Angeles Police Department said the three suspects waited for the people in the house to fall asleep, then woke them up at gun point around 4 a.m.
ABC7 was told electronics and jewelry were stolen from the partygoers, and the men jumped into a getaway car that was waiting for them on Mulholland Drive.
The house is gated and there's fencing around the property, which the suspects jumped over, authorities said.
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While police aren't sure if these suspects are part of a bigger home invasion ring, they are seeing an increase in brazen crimes.
The suspects are described as men in their 20s. There is a possible getaway car that was caught on a surveillance camera from another property along Mulholland around that time.
If you recognize the men in the video or the suspected getaway car, you're urged to call the LAPD.