The crash happened around midnight, prompting a complete shutdown of the westbound lanes. The woman was taken into custody at the scene.
Video obtained by Eyewitness News shows a bottle of Tito's vodka inside the vehicle she was driving, but it's unclear if the woman was driving under the influence.
A CHP officer was also seen holding a small plastic bag containing unknown materials.
One person was taken to the hospital with minor injuries.
The incident remains under investigation.