Los Angeles County Fire Department paramedics responded to the area near Palos Verdes Drive and West Calle Entradero around 2:40 p.m. to a report of a vehicle over a cliff.
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First responders arrived to the scene to search for any other potential victims after the car landed on a rocky beach, but there were no immediate reports of any other injuries.
One occupant of the vehicle was pronounced dead at the scene, according to a county fire spokesman.
Further details about the crash, including what caused the driver to go over the cliff, were not immediately released.
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City News Service contributed to this report.