The shooting was reported just after 1 a.m. inside Proof Bar located in the 200 block of North Broadway.
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Investigators said the suspect, who was identified as 22-year-old Armando Alvarez, took off but was later detained and arrested about a block away from the bar. He has since been booked into the Santa Ana Jail for attempted murder.
Meanwhile, the woman is currently in "critical yet stable" condition.
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It's unclear what led up to the shooting. Police said a firearm was recovered at the scene.
Anyone with information is urged to contact SAPD Homicide Section Detectives at 714-245-8390 or Orange County Crime Stoppers at 1-855-TIP-OCCS.