Officials allege Gina Murry, 32, a teacher at Esteban Torres High School, sexually assaulted the 15-year-old male student over a two-month period beginning in May.
Murry is facing charges that include six counts of unlawful sexual intercourse and four counts each of lewd act upon a child, oral copulation of a person under 16 and sexual penetration by a foreign object.
If convicted of all charges, Murry faces up to 17 years in state prison.