"We have made the difficult decision to divorce,'' the couple said in a joint statement provided to Page Six. "As two people that love and care for one another very much, we politely ask for privacy at this time as we navigate this new phase of our lives."
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The couple married in November 2015 after a whirlwind romance.
Rumors about their relationship began swirling in recent weeks, most notably when Vergara traveled to Italy to celebrate her 51st birthday without her husband.
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The marriage is the second for Vergara, but the first for Manganiello, 46.