At least three vehicles were involved in the collision, which occurred shortly before 1 a.m. at the intersection of Imperial Highway and Paramount Boulevard, a spokesperson for the Downey Police Department said.
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A preliminary investigation indicated two of those vehicles were possibly racing before the crash, the spokesperson said. News video from the scene showed a dark-colored vehicle overturned onto its roof, a heavily damaged white sedan, and a mangled pickup truck.
Five people were transported to multiple hospitals after the pileup, authorities said. Details about the injured and their conditions were not immediately available.
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One person was arrested on suspicion of felony reckless driving and hit-and-run, police said. Whether the suspect was among those hospitalized was unclear.