The crash was reported around 5:30 p.m.
Preliminary reports indicate the vehicle involved in the crash was traveling on the southbound side but overturned and landed on the northbound side.
At least one person was reported trapped in a vehicle initially and listed in critical condition.
The northbound freeway remained shut down for more than an hour, with all lanes reopening by 6:45 p.m.
Southbound lanes were not closed.