The crash happened around 9 p.m. in the 16000 block of Vanowen Street.
Los Angeles police said the teen made a turn from Odesa Avenue onto Vanowen when he was hit by another vehicle going eastbound.
The teen was pronounced dead at the scene.
Video from the crash shows the driver's side of a car with extensive damage.
The other driver suffered minor injuries and is cooperating in the investigation.
Police are still investigating who was at fault.