The crash occurred around 3:30 p.m. near Loma Drive and Third Street.
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The bus caused minor damage when it rolled backward into the wall, and the three passengers and driver were sent to the hospital with minor injuries, authorities said.
Metro issued a statement, saying the bus operator was fixing a mechanical issue outside his bus when the bus rolled back. About 15 to 20 people were onboard at the time.
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The Los Angeles Police Department is investigating the incident.