The 14-vehicle chain-reaction pileup occurred about 9 a.m. at Oak Hill Road and left most of the victims with moderate to minor injuries, according to the county fire department, which performed triage at the crash site.
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The majority of the patients declined to be transported to a hospital, according to fire officials. Two were taken to a medical center with unspecified injuries.
19-vehicle crash on 15 Freeway in Cajon Pass leaves dozens injured; all SB lanes closed
Heavy fog, reduced visibility and speed were believed to be contributing factors to the collision, which began when a vehicle spun out and others swerved in an attempt to avoid it, investigators said. Visibility was poor in the area due to heavy fog.
A miles-long backup of traffic ensued as California Highway Patrol and Caltrans personnel worked to clear the roadway. Several cars and at least three big rigs were heavily damaged in the wreck.
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Drivers stuck in the mess were frustrated.
"It's bad," said Compton resident Antwon Long. "I'm going to keep it real with you all -- I drove on the side of the freeway to get right here."
Just eight months ago, there was a chain-reaction wreck that shut down the Cajon Pass after two cars spun out.
"It was really foggy and everything, but I didn't think this would happen again. I thought people would learn their lesson from last time," shared driver Mitch Robinson.
It was deja vu all over again for many drivers as CHP, Caltrans and tow trucks worked to clear the road and reopen the highway.
All lanes were reopened about 12 p.m., Caltrans said.