Video shows the two vehicles colliding at an intersection and one of vehicles then jumps the curb and hits the child and a woman, who were at the corner of the sidewalk alongside several other pedestrians.
The boy, Sebastian Morales, died at the hospital.
The collision occurred about 7:30 a.m. near the intersection of Nordhoff Street and Langdon Avenue, according to the Los Angeles Police Department.
A 2016 Honda HRV heading west on Nordhoff was making a left turn when it collided with a gray Toyota Camry, LAPD said.
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18-month-old boy in stroller dies after crash sends car careening onto North Hills sidewalk
The impact sent the Honda over the curb at the southeast corner of the intersection, crashing into the boy in the stroller and an adult woman standing on the sidewalk near a food cart.
The female pedestrian, not related to the boy, was treated at a local hospital.
The driver of the Honda stayed at the scene. The driver of the Toyota left the scene, but came forward to police later Sunday afternoon. The driver was interviewed but no arrests have been made in connection with the collision.
Anyone with information about the crash is asked to contact police at (818) 644-8034.