Officers around 5:30 a.m. responded to a report of shots fired at the Broadway Palace Apartments at 9th Street and Broadway, according to the Los Angeles Police Department.
The department quickly confirmed that it was not an active shooter situation.
Alfonso Figueroa was one of the tenants sheltering in place. He told Eyewitness News that he believes he heard dozens of shots.
AIR7 was overhead where several patrol vehicles could be seen stationed around the building, which could be as tall as 10 stories.
LAPD surrounds downtown apartment building after report of woman with rifle
Dozens of fire trucks and patrol vehicles remained on scene hours later as officers combed the building looking for evidence of a shooting
"It is floor by floor, and then we'll hold those floors to make sure that no one comes behind us... it just takes some time," said Capt. Mike Bland.
Around noon, police said they narrowed their search to a single floor where a suspect was believed to have been barricaded.
A short time after that, police confirmed that two suspects were taken into custody but additional details about the shooting or any weapons they may have had were not available.
No victims were found during the search of the apartment building.