All lanes were closed Wednesday morning, but Caltrans reopened all north and southbound lanes in the area as of Wednesday afternoon.
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At least 15 vehicles with flat tires were reported on the right shoulder of the freeway at 10 p.m. Tuesday near Valley Boulevard, according to a California Highway Patrol incident log.
No crashes or injuries were reported.
Caltrans offers reimbursement of up to $10,000 for damage to vehicles by potholes
The closure lasted overnight and snarled traffic during the morning commute. Motorists were being diverted off the freeway at Holt Avenue.
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Caltrans workers were seen filling potholes with gravel and using motorized air blowers on the holes after they were filled in.
A similar incident occurred last week, when more than 30 vehicles were damaged by potholes on the freeway at the same location.