Michael Fleming, 59, died at a local hospital on Sunday, according to the U.S. Bureau of Prisons, which operates the Federal Correctional Institution on Terminal Island.
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Fleming was sentenced in Wyoming and had been housed at Terminal Island since Jan. 31, 2017. He was serving a 20-year sentence for conspiracy to possess with intent to distribute methamphetamine.
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He tested positive for the virus on April 8 and was hospitalized three days later, according to the bureau, where his condition declined.
Fleming had pre-existing medical conditions that made him more vulnerable to COVID-19, the respiratory disease caused by the coronavirus, authorities said.
Another inmate at the facility, 73-year-old Bradley James Ghilarducci, died last week.
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The Federal Bureau of Prisons reports 57 inmates and four staff members have tested positive at the prison.
Terminal Island is a low-security facility with 1,078 male inmates.
City News Service contributed to this report.