The blaze, dubbed the Lime Fire, broke out Wednesday afternoon close to the Lake Piru campground, according to the Ventura County Fire Department.
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At least 75 firefighters were working to suppress the flames but fire officials said it has the potential to grow to 1,000 acres. Twenty-five structures are threatened.
Resources that were being used to fight the nearby Elizabeth Fire, which broke out earlier in the day and scorched 250 acres, are being redirected to assist with the Lime Fire.
Brush fire near Ventura burns 50 acres
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Evacuations are underway for the Piru Campground and some surrounding areas.
DEVELOPING: This story will be updated as more information becomes available.