The designation means the building's owner would need special approval to alter the exterior or interior of the building and may have to wait up to one year for a demolition permit.
Located at 5124 H. DeLongpre Ave., Bukowski's former home and three other bungalows around a courtyard were built between 1922 and 1926.
Bukowski lived on DeLongpre Avenue when he finished his first novel, "Post Office." He died in San Pedro in 1994.
Bukowski fan Lauren Everett is behind the preservation effort.