The chase apparently began when the car's driver refused to pull over for Fontana police, triggering the pursuit.
The chase ended at the scene of the shooting near the eastbound 10 Freeway and Milliken Avenue.
Aerial footage captured by AIR7 HD showed the suspect's vehicle on the freeway onramp and it appeared police vehicles had rammed into the side of the suspect vehicle.
The person shot was transported to a hospital in unknown condition, according to Fontana police. Two people - a male and a female - were in the car, but it was unclear who had been shot.
It was not immediately known what prompted officers to shoot.
No officers were injured in the incident.