Boyle Heights residents are calling for the permanent closure of the Lineage Logistics warehouse as cleanup efforts continue beyond a city-imposed deadline.
Protesters rallied outside the Los Angeles County Board of Supervisors' Office, calling for the Men's Central Jail to officially be shut down after a vote to close it passed in 2020.
The event was supposed to end at 5 p.m. Saturday, and the arrests were made after a dispersal order was given at 5:30 p.m.
Police said dispersal orders were issued and multiple people were detained after the "No Kings" rally in downtown Los Angeles on Saturday.
Organizers say more than 3,100 events have been registered in all 50 states and several other countries, with more than 9 million people expected.
Portions of the 101 Freeway were shut down ahead of dozens of "No Kings" protests that are planned across Southern California this weekend.