"The lesion is apparently very deep. They're afraid it may be into the bone, which would not be good," Blanchette said. "Before taking that drastic measure, they want to give it one last chance with some really powerful antibiotics."
Blanchette said the lesion has grown from an inch a couple of months ago to almost a foot.
Her husband, Prince Frederic Von Anhalt, said Gabor is being treated with antibiotics first, and a decision on whether to amputate the leg won't be made for two or three days.
In July, Gabor broke her hip and had hip replacement surgery. Since then, she's been hospitalized several times with life-threatening complications.
The Associated Press contributed to this report.